Answers to frequent questions

What makes our approach unique?

Healthy skin is maintained by a fine balance between the bacterial communities and our immune system capacity to control their growth and behavior. The problem arises when this balance is tipped in the bacterial favor, and the immune system loses its ability to adequately respond and control the bacterial invasion and tissue damage.

The essence of our approach is to select the proteins which bacteria use to invade human cells and hide from the immune system or escape control, and then use these proteins to strengthen the skin immune system and teach it to respond in a more effective way.

How does the immune system distinguish between ‘good’ and ‘bad’ bacteria that live on our skin?

The immune system works like an army that protects our body. Our skin has its own immune system which has a difficult task: to defend the skin at specific locations and under specific conditions which can turn skin colonizing microbes from our ‚friends’ to enemies. The conditions that induce a significantly higher rate of bacterial growth or metabolic activity can irritate skin or lead to changes in the way our immune system responds. For example, increased secretion of sebum within skin pores supports growth and increases metabolic activity of the acne-associated bacterium, P. acnes. Significant changes in P. acnes growth and behavior can lead to damage of the skin surface barrier that protects us from external environment. This ‘danger’ signal alerts skin immune responses which act to prevent P. acnes invasion of the skin interior and more serious infections. The same skin immune response would not occur if the bacteria would peacefully live on our skin surface without insulting our skin cells. Therefore, our immune system knows when to respond and how to keep our skin protected and healthy.

How safe can an immune therapy against P. acnes be?

We are selecting the proteins which are already produced by the bacteria on our skin. We purify these proteins as a high quality, sterile material which is then presented to skin immune cells in the most optimal way to teach them to build a more effective defense. By selecting the most effective bacterial proteins for training immune response, we can ensure that the response is limited only to the virulent bacterial factors and not causing any other unwanted activity against our own cells, or against the bacteria which do not express these proteins. The specificity of the immune response will ensure that the therapy is safe, because it works only when the bacterium trespasses or ‘misbehaves’.

When is our product going to be available on the market?

Development of any therapeutic product takes many years, because scientists cannot develop the product in their research labs. After several years of intense research discovery, the product has to be manufactured under highly controlled conditions and is extensively tested to ensure safety. Our product will be available on the market only after being tested in clinical trials. Our first clinical trial will begin soon, but subsequent additional clinical studies will take several more years to complete. We are sorry that this process cannot be speeded up, due to many regulations we have to observe.

Is it going to be available worldwide?

Yes, our product will be available in many different parts of the world.

How can we support you and help you in your efforts?

The best way you can help us is by sharing your stories, not giving up your hope and not letting acne take away your life enjoyment. We know that it may seem difficult, but together we will succeed.