Origimm Biotechnology

ProVaDis: Protection-based Vaccine Discovery

Scientific digests

Addressing challenges in the design of vaccines for the future

Little did Edward Jenner know, upon performing his „vaccination“ experiments in 18th century England, that his findings would change the course of medicine and lead to the first worldwide eradication of an infectious agent, the smallpox (Variola virus). A practice that was already known to the Chinese around the year 1000 AC, Jenner improved upon it by inoculating his gardener´s 8-year-old son in 1796 with a related virus that caused a milder form of the disease in cows and… Continue reading

The role of P. acnes in the pathogenesis of acne vulgaris

Acne vulgaris continues to burden every generation, and despite the multitude of the treatments and products on the market, there is still no magic formula that can guarantee a long-term benefit to all acne patients. Antibiotics are most common treatment. However they cannot be given long term. Furthermore, widespread use of antibiotics is thought to be a factor in the rise of antibiotic-resistant bacteria, possibly leading to greater harm than benefit. Vitamin A derivatives (isotretinoins) represent the second widely used… Continue reading